Genetically Engineered Elastin-based Biomaterials for Biomedical Applications
نویسندگان
چکیده
منابع مشابه
Elastin-based Biopolymers for Biomedical and Biotechnological Applications
Perhaps the most appealing opportunity is represented by gaining inspiration from nature for the precise tailoring of biomaterials with finely tuned unique functional properties. A very promising model is represented by Human Elastin-Like Polypeptides (HELP), repetitive artificial polypeptides based on pentaor hexapeptidic motifs that characterize elastin. These protein polymers retain several ...
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A nanofabrication method for the production of flexible core-shell structured silk elastin nanofibers is presented, based on an all-aqueous coaxial electrospinning process. In this process, silk fibroin (SF) and silk-elastin-like protein polymer (SELP), both in aqueous solution, with high and low viscosity, respectively, were used as the inner (core) and outer (shell) layers of the nanofibers. ...
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Elastin-like polypeptides (ELP) are artificial, genetically encodable biopolymers, belonging to elastomeric proteins, which are widespread in a wide range of living organisms. They are composed of a repeating pentapeptide sequence Val-Pro-Gly-Xaa-Gly, where the guest residue (Xaa) can be any naturally occurring amino acid except proline. These polymers undergo reversible phase transition that c...
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ژورنال
عنوان ژورنال: Current Medicinal Chemistry
سال: 2020
ISSN: 0929-8673
DOI: 10.2174/0929867325666180508094637